Valsartan/hydrochlorothiazide (By mouth)
Hydrochlorothiazide (hye-droe-klor-oh-THYE-a-zide), Valsartan (val-SAR-tan)
Treats high blood pressure. This medicine is a combination of an angiotensin receptor blocker (ARB) and a thiazide diuretic (water pill).
When This Medicine Should Not Be Used
How to Use This Medicine
- Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.
- Carefully follow your doctor's instructions about any special diet. Drink plenty of fluids if you exercise, sweat more than usual, or have diarrhea or vomiting.
- Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.
- Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.
- Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
- Do not use this medicine together with aliskiren if you have diabetes.
- Some medicines can affect how this medicine works. Tell your doctor if you also the following:
- Atropine, biperiden, carbamazepine, cholestyramine, colestipol, cyclophosphamide, cyclosporine, digoxin, lithium, methotrexate, rifampin, or ritonavir
- Another diuretic (water pill, such as amiloride, spironolactone, triamterene), insulin or an oral diabetes medicine, or an NSAID pain or arthritis medicine (such as aspirin, diclofenac, ibuprofen, naproxen)
- Ask your doctor before you use any medicine, supplement, or salt substitute that contains potassium.
- Alcohol, narcotic pain relievers, or sleeping pills may cause you to feel more lightheaded, dizzy, or faint when used with this medicine. Tell your doctor if you drink alcohol or use pain relievers or sleeping pills.
Warnings While Using This Medicine
- It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant.
- Tell your doctor if you are breastfeeding, or if you have kidney problems, liver disease, heart failure, diabetes, gallstones, gout, lupus, or a history of asthma or allergies. Tell your doctor if you had angioedema that was caused by a blood pressure medicine.
- This medicine may cause the following problems:
- Kidney problems
- New or worsening lupus
- High or low levels of calcium, magnesium, potassium, or sodium
- New or worsening gout
- Increased cholesterol levels
- This medicine could lower your blood pressure too much and cause you to feel dizzy or lightheaded. Sit or lie down if you feel dizzy. Stand up carefully.
- Do not stop using this medicine without asking your doctor, even if you feel well. This medicine will not cure your high blood pressure, but it will help keep it in the normal range. You may have to take blood pressure medicine for the rest of your life.
- Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
Possible Side Effects While Using This Medicine
Call your doctor right away if you notice any of these side effects:
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Blistering, peeling, red skin rash
- Change in how much or how often you urinate
- Confusion, weakness, uneven heartbeat, trouble breathing, numbness or tingling in your hands, feet, or legs
- Dry mouth, increased thirst, muscle cramps, nausea or vomiting, uneven heartbeat
- Fever, muscle pain, skin rash
- Lightheadedness, dizziness, fainting
- Rapid weight gain, swelling in your hands, ankles, or feet
- Trouble seeing, blurred vision, eye pain
If you notice these less serious side effects, talk with your doctor:
If you notice other side effects that you think are caused by this medicine, tell your doctor
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088
- Last reviewed on 8/4/2014
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