Palonosetron Hydrochloride (pal-oh-NOE-se-tron hye-droe-KLOR-ide)
Prevents nausea and vomiting caused by cancer treatments or surgery.
When This Medicine Should Not Be Used
How to Use This Medicine
- Your doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.
- A nurse or other health provider will give you this medicine.
- This medicine is usually given about 30 minutes before the start of chemotherapy or right before you receive anesthetic medicine for surgery.
- Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
Warnings While Using This Medicine
- Tell your doctor if you are pregnant or breastfeeding, or if you had an allergic reaction to similar medicines, such as alosetron, dolasetron, granisetron, or ondansetron.
- Check with your doctor if severe nausea and vomiting continue after you leave the hospital or cancer treatment center.
Possible Side Effects While Using This Medicine
Call your doctor right away if you notice any of these side effects:
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Fast, slow, or uneven heartbeat
- Lightheadedness, dizziness, or fainting
If you notice these less serious side effects, talk with your doctor:
- Pain, burning, redness, swelling, or a lump under your skin where the needle is placed
If you notice other side effects that you think are caused by this medicine, tell your doctor
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088
- Last reviewed on 8/4/2014
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