Olmesartan/hydrochlorothiazide (By mouth)
Hydrochlorothiazide (hye-droe-klor-oh-THYE-a-zide), Olmesartan Medoxomil (ol-me-SAR-tan me-DOX-oh-mil)
Treats high blood pressure. A lower blood pressure can reduce the risk of stroke and heart attack. This medicine contains an angiotensin receptor blocker (ARB) and a thiazide diuretic (water pill).
When This Medicine Should Not Be Used
How to Use This Medicine
- Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.
- Carefully follow your doctor's instructions about any special diet. Drink plenty of fluids if you exercise, sweat more than usual, or have diarrhea or vomiting.
How to Store and Dispose of This Medicine
- Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
- Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
- Make sure your doctor knows if you also use a diuretic (water pill, such as furosemide, hydrochlorothiazide, torsemide, Aldactone®, Demadex®, Lasix®, Zaroxolyn®) or other blood pressure medicine (such as aliskiren, benazepril, enalapril, lisinopril, Avalide®, Avapro®, Benicar®, Cozaar®, Diovan®, Lotrel®, Micardis®, Tekturna®, Vasotec®, Zestril®, Zestoretic®).
- Make sure your doctor knows if you also use lithium (Eskalith®, Lithobid®), medicine to lower cholesterol (such as cholestyramine, colestipol, Colestid®, Questran®), insulin or diabetes medicine that you take by mouth (such as glimepiride, glyburide, metformin, Actos®, Janumet®, Januvia®), a steroid medicine (such as dexamethasone, hydrocortisone, methylprednisolone, prednisolone, prednisone), or an NSAID pain or arthritis medicine (such as aspirin, diclofenac, ibuprofen, naproxen, Advil®, Aleve®, Celebrex®, Voltaren®).
- If you also use colesevelam (Welchol®), take it at least 4 hours after you take Benicar HCT®.
- Ask your doctor before you use any medicine, supplement, or salt substitute that contains potassium.
- Alcohol, narcotic pain relievers, or sleeping pills may cause you to feel more lightheaded, dizzy, or faint when used with this medicine.
Warnings While Using This Medicine
- It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant.
- Make sure your doctor knows if you are breastfeeding or if you have kidney problems, liver disease (including cirrhosis), congestive heart failure, diabetes, glaucoma, gout, high cholesterol, a mineral imbalance (such as high or low calcium, potassium, magnesium, or sodium in the blood), lupus, or asthma.
- This medicine could lower your blood pressure too much and cause you to feel dizzy or lightheaded. Stand or sit up slowly if you are dizzy. This is more likely to happen when you begin to use the medicine or if you become dehydrated.
- Severe chronic diarrhea with weight loss may develop months to years after you start taking this medicine. Tell your doctor right away if you have these symptoms.
- Check with your doctor immediately if you have vision changes, such as blurred vision, trouble reading, or eye pain, during or after treatment. This could be a sign of a serious eye problem.
- Do not stop using the medicine without asking your doctor, even if you feel well. This medicine will not cure your high blood pressure, but it will help keep it in normal range. You may have to take blood pressure medicine for the rest of your life.
- Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
Possible Side Effects While Using This Medicine
Call your doctor right away if you notice any of these side effects:
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Blistering, peeling, or red skin rash
- Blurred vision or changes in vision, eye pain
- Change in how much or how often you urinate, bloody or cloudy urine
- Confusion, weakness, and muscle twitching
- Dry mouth, increased thirst, muscle cramps, nausea, vomiting
- Fast, slow, or uneven heartbeat, chest pain
- Lightheadedness, dizziness, or fainting
- Severe diarrhea with weight loss
If you notice these less serious side effects, talk with your doctor:
- Cough, runny or stuffy nose, sore throat
If you notice other side effects that you think are caused by this medicine, tell your doctor
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088
- Last reviewed on 8/4/2014
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