Ioflupane I 123 (Injection)


Ioflupane I 123 (eye-oh-FLOO-pane I 123)

Used in adults to help diagnose Parkinsonian syndromes during a procedure called a single photon emission computed tomography (SPECT) scan.

Brand Name(s)


When This Medicine Should Not Be Used

How to Use This Medicine


  • A doctor or other trained health professional will give you this medicine. This medicine is given through a needle placed in one of your veins just before you have a SPECT scan.
  • You will need to urinate right away and as often as possible for 48 hours after receiving this medicine. Drink plenty of fluids before and after receiving this medicine so you will pass more urine.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are also using amphetamine, benztropine (Cogentin®), buspirone (BuSpar®), cocaine, mazindol (Mazanor®, Sanorex®), methamphetamine (Desoxyn®), methylphenidate (Methylin®, Ritalin®), norephedrine, phentermine (Zantryl®), phenylpropanolamine, or medicine to treat depression (such as amoxapine, bupropion, citalopram, paroxetine, selegiline, sertraline, Asendin®, Celexa®, Eldepryl®, Paxil®, Wellbutrin®, Zoloft®, or Zyban®).

Warnings While Using This Medicine

  • Make sure your doctor knows if you are pregnant or breastfeeding, or if you have kidney disease.
  • This medicine may cause allergic reactions. Tell your doctor right away if you have difficulty with breathing or swallowing; fever; hives; itching skin; nausea; reddening of the skin, especially around the ears; swelling of the eyes, face, or inside of the nose; or unusual tiredness or weakness after you have receive this medicine.
  • While receiving this medicine, you will be exposed to radiation. If you have any questions about this, talk to your doctor.
  • You will receive a medicine such as potassium iodide, Lugol's solution, or potassium perchlorate before receiving Ioflupane I 123. These medicines will help protect your thyroid gland from radiation (iodine 123). Tell your doctor if you have had an allergic reaction to these medicines or other products containing iodine.
  • Your doctor will check your progress very closely while you are receiving this medicine. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to receive it.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Pain, itching, burning, swelling, or a lump under your skin where the needle is placed.
  • Redness of the skin, rash, or itching skin.

If you notice these less serious side effects, talk with your doctor:

  • Dizziness or lightheadedness.
  • Dry mouth.
  • Feeling of constant movement of self or surroundings.
  • Headache.
  • Nausea.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Version Info

  • Last reviewed on 8/4/2014

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