Ibuprofen lysine (Injection)


Ibuprofen Lysine (eye-bue-PROE-fen LYE-seen)

Treats a heart condition known as patent ductus arteriosus (PDA) in premature babies.

Brand Name(s)


When This Medicine Should Not Be Used

How to Use This Medicine


  • A nurse or other trained health professional will give your child this medicine.
  • This medicine is given to your child through a needle placed in one of the veins.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your child's doctor knows about all the medicines your child is receiving.

Warnings While Using This Medicine

  • Make sure your child's doctor knows if your child has any infection, liver disease, bleeding disorder, or bleeding in the brain, stomach, or intestines.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your child's face or hands, swelling or tingling in your child's mouth or throat, chest tightness, trouble breathing.
  • Absence of bowel movement or stools.
  • Bulge or lump on your child's groin.
  • Fast, slow, or uneven heartbeat.
  • High fever and chills.
  • Red or dark brown urine, or change in the number of wet diapers each day.
  • Seizures.
  • Severe vomiting or bloated belly.
  • Swelling in your child's hands, ankles, or feet.
  • Trouble breathing, or bluish-colored skin.
  • Unusual bleeding, bruising, or weakness.
  • Yellowing of the skin or the whites of your child's eyes.

If you notice these less serious side effects, talk with your doctor:

  • Diarrhea or vomiting.
  • Poor feeding.
  • Redness, swelling, rash, or a lump under your child's skin where the needle is placed.
  • Runny or stuffy nose.
  • Skin rash.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Version Info

  • Last reviewed on 8/4/2014

A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org). URAC's accreditation program is an independent audit to verify that A.D.A.M. follows rigorous standards of quality and accountability. A.D.A.M. is among the first to achieve this important distinction for online health information and services. Learn more about A.D.A.M.'s editorial policy, editorial process and privacy policy. A.D.A.M. is also a founding member of Hi-Ethics and subscribes to the principles of the Health on the Net Foundation (www.hon.ch)

The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- 2013 A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.