Hyoscyamine sulfate (Injection)


Hyoscyamine Sulfate (hye-oh-SYE-a-meen SUL-fate)

Treats many conditions of the stomach, kidneys, or bladder. Used in anesthesia during surgery. Also used during a medical test or imaging procedure to help internal organs or other body parts show up better.

Brand Name(s)


When This Medicine Should Not Be Used

How to Use This Medicine


  • Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot under your skin, into a muscle, or into a vein.
  • A nurse or other health provider will give you this medicine.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are using medicines such as amantadine, haloperidol (Haldol®, Clozaril®), MAO inhibitors (Eldepryl®, Marplan®, or Nardil®), phenothiazines (Prochloroperazine®, Compazine®, or Phenergan®), tricyclic antidepressants (amitriptyline or Norpramin®), antimuscarinics (Bentyl®, or Robinul®) or medicine for allergy.

Warnings While Using This Medicine

  • Make sure your doctor knows if you are pregnant or breast feeding.
  • Make sure your doctor knows if you have heart disease, high blood pressure, kidney disease, or thyroid disease.
  • This medicine may make you drowsy. Avoid driving, using machines, or doing anything else that could be dangerous if you are not alert.
  • This medicine may make you sweat less, this can be dangerous if you get too hot.
  • Make sure your doctor knows if you have had severe diarrhea or hiatus hernia.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Blurred vision.
  • Confusion, drowsiness, dizziness, or headache.
  • Decrease in how much or how often you urinate.
  • Fast or strong heartbeat.
  • Problems with your speech.

If you notice these less serious side effects, talk with your doctor:

  • Decrease in your breast milk.
  • Decreased sweating, dry mouth, or loss of taste.
  • Nausea, vomiting, or Constipation.
  • Trouble having sex (in men).
  • Trouble sleeping, or feeling excited.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Version Info

  • Last reviewed on 8/4/2014

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