Guaifenesin/hydrocodone (By mouth)

Introduction

Guaifenesin (gwye-FEN-e-sin), Hydrocodone (hye-droe-KOE-done)

Treats cough. This medicine contains a narcotic cough medicine.

Brand Name(s)

Xpect-HC

When This Medicine Should Not Be Used

How to Use This Medicine

Liquid, Capsule, Long Acting Tablet

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.
  • Measure the oral liquid medicine with a marked measuring spoon, oral syringe, or medicine cup.
  • Swallow the extended-release tablet whole. Do not crush, break, or chew it.
  • Drink plenty of liquids to help avoid constipation.

If a dose is missed:

  • Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

How to Store and Dispose of This Medicine

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
  • Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are also using pain or arthritis medicine such as diclofenac, etodolac, indomethacin, Daypro®, Dolobid®, Feldene®, Indocin®, Relafen®, Voltaren®.
  • Make sure your doctor knows if you are using a phenothiazine medicine such as Compazine®, Phenergan®, Serentil®, or Thorazine®.
  • Tell your doctor if you drink alcohol or if you are using any medicine that makes you sleepy, such as allergy medicine or narcotic pain medicine.
  • Do not drink alcohol while you are using this medicine.

Warnings While Using This Medicine

  • Make sure your doctor knows if you are pregnant or breast feeding.
  • Make sure your doctor knows if you have recently had any head injury or stomach problems.
  • Make sure your doctor knows if you have a history of mental illness, alcoholism, or drug addiction problem.
  • This medicine can be habit-forming. Do not use more than your prescribed dose. Call your doctor if you think your medicine is not working.
  • This medicine may make you dizzy or drowsy. Avoid driving, using machines, or doing anything else that could be dangerous if you are not alert.
  • Tell any doctor or dentist who treats you that you are using this medicine. You may need to stop using this medicine several days before you have surgery or medical tests. Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.
  • This medicine may cause constipation, especially with long-term use. Ask your doctor if you should use a laxative to prevent and treat constipation.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Blurred vision.
  • Change in how much or how often you urinate.
  • Light-headedness or fainting.
  • Pain while passing urine.
  • Pounding heartbeat.
  • Severe headache.
  • Trouble breathing.

If you notice these less serious side effects, talk with your doctor:

  • Anxiety or mood changes.
  • Confusion or fear.
  • Mild nausea or vomiting.
  • Weakness.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Version Info

  • Last reviewed on 8/4/2014

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