Etravirine (By mouth)
Treats human immunodeficiency virus (HIV) infection. HIV causes acquired immune deficiency syndrome (AIDS). Etravirine does not cure HIV or AIDS, but it may slow the progress of the disease.
When This Medicine Should Not Be Used
How to Use This Medicine
- Take your medicine as directed.
- Etravirine is used with other medicines to treat HIV infection. Take all of your medicines as your doctor has prescribed. Do not change your dose or stop taking this medicine unless your doctor tells you to.
- This medicine works best if there is a constant amount in the blood. Take this medicine at the same time each day and do not miss any doses. Contact your doctor or pharmacist when your supply of this medicine is running low. Do not let your medicine run out.
- It is best to take this medicine with food or milk.
- Swallow the tablet whole. Do not chew it.
- If you cannot swallow the tablet, you may dissolve it in a glass with a small amount of water. You may then add more water, orange juice, or milk to make it easier to take. Do not use grapefruit juice or warm or carbonated drinks. Be sure to drink the entire mixture right away. Then refill your glass with water, orange juice, or milk and drink it so that none of the medicine is left in the glass.
- Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.
If a dose is missed:
- If you miss a dose or forget to take your medicine and it is less than 6 hours from the time your regular dose was scheduled, take the tablet as soon as you can. If you miss a dose and it is more than 6 hours from the time your regular dose was scheduled, skip the missed dose and take your next dose at the regular time. Do not use extra medicine to make up for a missed dose.
How to Store and Dispose of This Medicine
- Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
- Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
- Make sure your doctor knows if you use St John's wort, other medicines to treat HIV or AIDS (such as atazanavir, atazanavir/ritonavir, darunavir/ritonavir, delavirdine, efavirenz, fosamprenavir, fosamprenavir/ritonavir, indinavir, lopinavir/ritonavir, nelfinavir, nevirapine, rilpivirine, ritonavir, saquinavir/ritonavir, tipranavir/ritonavir, Atripla®, Crixivan®, Kaletra®, Lexiva®, Norvir®, Prezista®, Rescriptor®, Reyataz®, Sustiva®), or medicine to prevent blood clots (such as clopidogrel, Plavix®).
- Tell your doctor if you use medicine for a heart rhythm problem (such as amiodarone, bepridil, digoxin, disopyramide, flecainide, lidocaine, mexiletine, propafenone, quinidine, Cordarone®, Lanoxin®, Norpace®, Rythmol SR®, Tambocor®), a blood thinner (such as warfarin, Coumadin®, Jantoven®), medicine to treat seizures (such as carbamazepine, diazepam, phenobarbital, phenytoin, Dilantin®, Tegretol®), medicine to treat a fungal infection (such as fluconazole, itraconazole, ketoconazole, posaconazole, voriconazole, Diflucan®, Nizoral®), medicine to treat an infection (such as clarithromycin, rifabutin, rifampin, rifapentine, Mycobutin®, Priftin®, Rifadin®, Rifamate®, Rifater®), or medicine to treat malaria (such as artemether/lumefantrine, Coartem®).
- Make sure your doctor knows if you use a steroid medicine (such as dexamethasone, Decadron®), medicine to lower cholesterol (such as atorvastatin, fluvastatin, lovastatin, pitavastatin, simvastatin, Lipitor®, Vytorin®, Zocor®), medicine that weakens the immune system (such as cyclosporine, sirolimus, tacrolimus, Gengraf®, Neoral®, Prograf®, Rapamune®, Sandimmune®), a pain medicine (such as buprenorphine, buprenorphine/naloxone, methadone, Buprenex®, Dolophine®, Suboxone®), or medicine to treat impotence (such as sildenafil, tadalafil, vardenafil, Cialis®, Levitra®, Viagra®).
Warnings While Using This Medicine
- Make sure your doctor knows if you are pregnant or if you have liver disease (including hepatitis B or C).
- Do not breastfeed. You can spread HIV or AIDS to your baby through your breast milk.
- This medicine will not keep you from giving HIV to others. Always practice safe sex, even if your partner also has HIV. Do not share needles or other items that may have blood or body fluids on them.
- Your immune system may get stronger when you start taking HIV medicines. Tell your doctor right away if you notice any changes in your health. Sometimes the immune system will start to fight infections that were hidden in your body, such as pneumonia, herpes, or tuberculosis. Autoimmune disorders such as Graves disease, polymyositis, and Guillain-Barré syndrome may also occur.
- Serious skin reactions can occur with this medicine. Check with your doctor right away if you have blistering, peeling, or loose skin, fever, chills, joint or muscle pain, rash, sores, ulcers, or red skin lesions, or swelling of your hands, face, tongue, or throat.
- This medicine may cause changes to your body fat. Tell your doctor if you notice changes in your body shape, such as more fat in your upper back and neck or around your chest and stomach area. You may also lose fat from your legs, arms, and face.
- Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
Possible Side Effects While Using This Medicine
Call your doctor right away if you notice any of these side effects:
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Blistering, peeling, or red skin rash
- Dark-colored urine or pale stools, nausea, vomiting, loss or appetite, pain in your upper stomach, yellow skin or eyes
- Fever, chills, cough, sore throat, and body aches
- Swelling of your face, hands, or feet
- Unusual tiredness or weakness
If you notice these less serious side effects, talk with your doctor:
- Mild skin rash
- Weight gain around your neck, upper back, breast, or waist
If you notice other side effects that you think are caused by this medicine, tell your doctor
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088
- Last reviewed on 8/4/2014
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