Digoxin (Injection)


Digoxin (di-JOX-in)

Treats heart failure and heart rhythm problems (such as atrial fibrillation). This medicine is also called digitalis.

Brand Name(s)

Lanoxin, Lanoxin Pediatric

When This Medicine Should Not Be Used

How to Use This Medicine


  • Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot into a muscle or into a vein.
  • A nurse or other health provider will give you this medicine.
  • Your doctor may give you a few doses of this medicine until your condition improves, and then you may be switched to an oral medicine that works the same way. If you have any concerns about this, talk to your doctor.

If a dose is missed:

  • Call your doctor or pharmacist for instructions.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor know if you are also using any other medicine for heart rhythm problems (such as amiodarone, dofetilide, dronedarone, propafenone, quinidine, sotalol).
  • Make sure your doctor knows if you are also using ginseng, quinine, ritonavir (Norvir®), spironolactone (Aldactone®), dopamine (Intropin®), teriparatide (Forteo®), thyroid medicine (such as levothyroxine), or blood pressure medicine (such as atenolol, metoprolol, propranolol, amlodipine, diltiazem, verapamil).

Warnings While Using This Medicine

  • Make sure your doctor knows if you are pregnant or breastfeeding, or if you have any other heart problems, including heart block, recent heart attack, or Wolff-Parkinson-White syndrome. Tell your doctor if you have kidney disease, liver disease, blood vessel disease, thyroid problems, or high or low calcium, magnesium or potassium levels in your blood.
  • This medicine has been associated with the following problems.
    • Overdose
    • Slow heartbeat, heart block
  • Make sure any doctor or dentist who treats you knows that you are using this medicine.
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Confusion, weakness, headache, dizziness
  • Fast, slow, pounding, or uneven heartbeat
  • Nausea, vomiting, loss of appetite, ongoing diarrhea, blurred vision, yellow-colored vision
  • Weight loss, stomach pain, unusual behavior, drowsiness (in children)

If you notice these less serious side effects, talk with your doctor:

  • Pain, itching, burning, swelling, or a lump under your skin where the needle or shot was given

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Version Info

  • Last reviewed on 8/4/2014

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