Dicyclomine (Injection)


Dicyclomine (dye-SYE-kloe-meen)

Treats irritable bowel syndrome, or spastic colon and colitis. This medicine is given to people who cannot take dicyclomine by mouth.

Brand Name(s)

Bentyl, Dicyclocot

When This Medicine Should Not Be Used

How to Use This Medicine


  • Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot into one of your muscles.
  • A nurse or other health provider will give you this medicine.
  • This IM form of dicyclomine is not for long-term use. Your doctor might have you switch to dicyclomine that you take by mouth as soon as you are able.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are using amantadine (Symmetrel®), digoxin (Lanoxin®), or a belladonna medicine such as atropine, hyoscyamine, scopolamine, Anaspaz®, Arco-Lase® Plus, or Donnatal®. Tell your doctor if you are using an MAO inhibitor such as Eldepryl®, Marplan®, Nardil®, or Parnate®.
  • Tell your doctor if you are also using narcotic pain medicine, medicine for heart rhythm problems, an antihistamine, medicine to treat depression, phenothiazines (medicines to treat certain mental problems or severe nausea or vomiting), or a steroid medicine. Meperidine (Demerol®) is a narcotic pain medicine. Some medicines for heart rhythm problems are disopyramide, procainamide, quinidine, Cardioquin®, Norpace®, Procanbid®, or Quinaglute®. Diphenhydramine (Benadryl®) is an antihistamine. Some phenothiazine medicines are Compazine®, Mellaril®, Phenergan®, Serentil®, Tacaryl®, Thorazine®, or Trilafon®. Some medicines to treat depression are amitriptyline, nortriptyline, Norpramin®, or Vivactil®. Cortisone and prednisone are steroid medicines.

Warnings While Using This Medicine

  • Make sure your doctor knows if you are pregnant, if you have liver disease, kidney disease, or overactive thyroid. Tell your doctor about any heart or blood vessel problems you have, including heart rhythm problems, congestive heart failure, or high blood pressure. Make sure your doctor knows if you have ongoing diarrhea, or an ileostomy or colostomy. Tell your doctor if you have autonomic neuropathy (a nerve problem), or a hiatal hernia (problems with your esophagus).
  • This medicine may make you sweat less. Your body could get too hot if you do not sweat enough. Stay out of hot places. Try to stay indoors or somewhere cool during hot weather. If you have a fever, call your doctor for advice. If your body gets too hot, you might feel dizzy, weak, tired, or confused. You might have an upset stomach or vomit. Call your doctor if you are too hot and cannot cool down.
  • This medicine may make you drowsy. Avoid driving, using machines, or doing anything else that could be dangerous if you are not alert.
  • Your eyes may be more sensitive to bright light while you are using this medicine. You may want to wear sunglasses in bright sunlight.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Fast or uneven heartbeat.
  • Restlessness, agitation, or confusion.
  • Severe dizziness or light-headedness.

If you notice these less serious side effects, talk with your doctor:

  • Decrease in how much or how often you urinate.
  • Drowsiness or weakness.
  • Dry mouth.
  • Nausea, vomiting, constipation, or stomach pain.
  • Pain or swelling at your injection site.
  • Trouble focusing or other vision changes.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Version Info

  • Last reviewed on 8/4/2014

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