Cyclopentolate/phenylephrine (Into the eye)


Cyclopentolate (sye-kloe-PEN-toe-late), Phenylephrine (fen-il-EF-rin)

Used to dilate your eyes (make your pupils bigger).

Brand Name(s)


When This Medicine Should Not Be Used

How to Use This Medicine

Liquid, Drop

  • Take your medicine as directed.
  • If you are giving this medicine to a baby or child, make sure you do not get any medicine in the baby's or child's mouth. Wash your hands and your child's or baby's hands with soap and water before and after using this medicine. You should not feed your baby for 4 hours after they receive this medicine.
  • Lie down or tilt your head back. With your index finger, pull down the lower lid of your eye to form a pocket.
  • Hold the dropper close to your eye with the other hand. Drop the correct number of drops into the pocket made between your lower lid and eyeball. Gently close your eyes. Place your index finger over the inner corner of your eye for 2 to 3 minutes (this is very important if you are giving this medicine to a baby or child). Do not rinse or wipe the dropper or allow it to touch anything, including your eye. Put the cap on the bottle right away. Keep the bottle upright when you are not using it.
  • This medicine is not for long-term use.

If a dose is missed:

  • Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

How to Store and Dispose of This Medicine

  • Store the medicine at room temperature, away from heat and direct light.
  • Ask your pharmacist, doctor, or health caregiver about the best way to dispose of the used medicine container and any leftover medicine after you have finished your treatment. You will also need to throw away old medicine after the expiration date has passed.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are using any medicine for glaucoma such as carbachol, pilocarpine, Miostat®, or Pilopine HS®. Ask your doctor before you use any other medicine in your eyes.

Warnings While Using This Medicine

  • Make sure your doctor knows if you are pregnant or breast feeding. Tell your doctor if you have an overactive thyroid, heart disease, high blood pressure, or Down's syndrome.
  • Babies and children are more likely to have side effects from this medicine. If you are giving this medicine to an infant, watch the baby closely for at least 30 minutes after you give the medicine. Call your baby's or child's doctor if you notice any unusual behavior or if they have trouble moving or speaking.
  • If this medicine is being given to a child, make sure the doctor knows if the child has Down's syndrome, brain damage, or spastic paralysis (a disorder of the muscles and nerves).
  • Avoid driving, using machines, or doing anything else that could be dangerous if you cannot see well.
  • This medicine will make your eyes sensitive to light. Wear sunglasses if you go outside.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Dizziness, trouble walking, or feeling unsteady.
  • Eye burning or watering that does not go away.
  • Eye redness, pain, or swelling.
  • Hallucinations (seeing things that are not there).
  • High fever or fast heartbeat.
  • Rash or itching around your eyes.
  • Unusual behavior, confusion, or nervousness.

If you notice these less serious side effects, talk with your doctor:

  • Constipation, or urinating less than usual.
  • Dry mouth.
  • Mild burning feeling in your eyes.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Version Info

  • Last reviewed on 8/4/2014

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