Capreomycin (Injection)


Capreomycin (kap-ree-oh-MYE-sin)

Treats tuberculosis (TB).

Brand Name(s)

Capastat Sulfate

When This Medicine Should Not Be Used

How to Use This Medicine


  • Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot into one of your muscles.
  • Take all of the medicine in your prescription to clear up your infection, even if you feel better after the first few doses.
  • A nurse or other health provider will give you this medicine.
  • You may be taught how to give your medicine at home. Make sure you understand all instructions before giving yourself an injection. Do not use more medicine or use it more often than your doctor tells you to.
  • Missed dose: Call your doctor or pharmacist for instructions.
  • This medicine is mixed with another liquid (usually sterile water or sodium chloride solution) before it is given. After the medicine is mixed, you can keep it at room temperature for 2 days or for 14 days in the refrigerator.
  • Check the medicine before each use. Do not use it if you see solid pieces or specks in the liquid.
  • If you have your treatments at home, you should be given a container for the used needles and syringes. Keep it where children or pets cannot reach it.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Some medicines can affect how capreomycin works. Tell your doctor if you are being given injections of amikacin, gentamicin, kanamycin, netilmicin, streptomycin, tobramycin, or vancomycin.

Warnings While Using This Medicine

  • Tell your doctor if you are pregnant or breastfeeding, or if you have hearing problems, kidney disease, or any allergies, especially any allergic reactions to medicine.
  • This medicine may cause hearing loss. Your doctor may want to test your hearing before you start taking capreomycin and while you are taking it.
  • Capreomycin may also cause problems with your kidneys. You may need to have blood tests to make sure your kidneys are working properly before and during the time you are given this medicine.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone. Do not share your needles or syringes with anyone.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Fever, chills, or sore throat
  • Hearing loss, ringing in your ears, or dizziness
  • Heavy bleeding or a lump where the shot is given
  • Muscle weakness
  • Trouble breathing
  • Urinating little or nothing
  • Unusual bleeding or bruising

If you notice these less serious side effects, talk with your doctor:

  • Pain where the shot is given

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Version Info

  • Last reviewed on 8/4/2014

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