Candesartan/hydrochlorothiazide (By mouth)
Candesartan Cilexetil (kan-de-SAR-tan sye-LEX-e-til), Hydrochlorothiazide (hye-droe-klor-oh-THYE-a-zide)
Treats high blood pressure. A lower blood pressure can reduce the risk of stroke and heart attack. This medicine contains an angiotensin receptor blocker and a thiazide diuretic (water pill).
When This Medicine Should Not Be Used
How to Use This Medicine
- Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.
- Carefully follow your doctor's instructions about any special diet. Drink plenty of fluids if you exercise, sweat more than usual, or have diarrhea or vomiting.
If a dose is missed:
- Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.
How to Store and Dispose of This Medicine
- Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
- Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
- Make sure your doctor knows if you are also using other blood pressure medicine (such as aliskiren, benazepril, enalapril, lisinopril, Avalide®, Avapro®, Lotrel®, Vasotec®, Zestril®, Zestoretic®) or a diuretic (water pill, such as furosemide, spironolactone, torsemide, triamterene, Lasix®).
- Make sure your doctor knows if you are also using digoxin (Digitek®, Lanoxin®), lithium (Eskalith®, Lithobid®), insulin or a diabetes medicine that you take by mouth (such as glimepiride, glyburide, metformin, Actos®, Janumet®, Januvia®), or an NSAID pain or arthritis medicine (such as aspirin, diclofenac, ibuprofen, naproxen, Advil®, Aleve®, Celebrex®, Voltaren®).
- Tell your doctor if you also take medicine to lower your cholesterol (such as cholestyramine, colestipol, Colestid®, Questran®). You may need allow at least 4 hours between the times that you take these 2 medicines.
- Ask your doctor before you use any medicine, supplement, or salt substitute that contains potassium.
- Alcohol, narcotic pain relievers, or sleeping pills may cause you to feel more lightheaded, dizzy, or faint when used with this medicine. Tell your doctor if you drink alcohol or use pain relievers or sleeping pills.
Warnings While Using This Medicine
- It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant.
- Make sure your doctor knows if you are breastfeeding, or if you have kidney problems, liver disease, heart or blood vessel disease, congestive heart failure, low blood pressure, high cholesterol or triglycerides, or a mineral imbalance (such as high or low calcium, magnesium, potassium, or sodium in the blood). Tell your doctor if you have diabetes, gout, lupus, allergies, or a history of asthma.
- This medicine could lower your blood pressure too much and cause you to feel dizzy or lightheaded. Stand or sit up slowly if you are dizzy. This is more likely to happen when you begin to use the medicine or if you become dehydrated.
- Check with your doctor right away if you have confusion, muscle pain or cramps, nausea and vomiting, trouble breathing, weakness, or an uneven heartbeat. These could be symptoms of electrolyte imbalances (too little sodium, potassium, or magnesium).
- Check with your doctor immediately if blurred vision, difficulty reading, eye pain, or any other change in vision occurs.
- This medicine may change your blood sugar levels. If you are diabetic, you may need to check your blood sugar more often.
- Do not stop using this medicine without asking your doctor, even if you feel well. This medicine will not cure your high blood pressure, but it will help keep it in normal range. You may have to take blood pressure medicine for the rest of your life.
- Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
Possible Side Effects While Using This Medicine
Call your doctor right away if you notice any of these side effects:
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Blurred vision and eye pain
- Change in how much or how often you urinate, problems urinating
- Chest pain
- Confusion, weakness, uneven heartbeat, trouble breathing, numbness or tingling in your hands, feet, or lips
- Dark-colored urine or pale stools, nausea, vomiting, loss of appetite, pain in your upper stomach, yellow skin or eyes
- Dry mouth, increased thirst, muscle cramps, nausea or vomiting, uneven heartbeat
- Fast, slow, or pounding heartbeat
- Lightheadedness, dizziness, or fainting
- Rapid weight gain, swelling in your hands, ankles, or feet
- Unusual tiredness or weakness
If you notice other side effects that you think are caused by this medicine, tell your doctor
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088
- Last reviewed on 8/4/2014
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