Almotriptan (By mouth)


Almotriptan (al-moe-TRIP-tan)

Treats migraine headaches.

Brand Name(s)


When This Medicine Should Not Be Used

How to Use This Medicine


  • Take your medicine as directed.
  • When you feel a migraine headache starting, take 1 dose of this medicine.
  • If your headache improves but then comes back, you may take a second dose. Wait at least 2 hours before you take the second dose.
  • If your headache does not improve at all after the first dose, do not take a second dose. Call your doctor.
  • Do not use more than 2 doses in any 24-hour period. Do not use this medicine for more than 4 headaches in any 30-day period, unless your doctor tells you to.
  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.
  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Do not take almotriptan within 24 hours of taking another migraine headache medicine, such as dihydroergotamine, ergotamine, methysergide, naratriptan, rizatriptan, sumatriptan, or zolmitriptan.
  • Some medicines can affect how almotriptan works. Tell your doctor if you are taking any of the following:
    • An MAO inhibitor
    • Antibiotic medicine, such as erythromycin
    • Medicine to treat depression, such as citalopram, duloxetine, escitalopram, fluoxetine, fluvoxamine, paroxetine, sertraline, venlafaxine
    • Medicine to treat fungal infections, such as itraconazole, ketoconazole
    • Medicine to treat HIV/AIDS, such as ritonavir

Warnings While Using This Medicine

  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney or liver disease, bleeding problems, high blood pressure, or a family history of heart disease. Tell your doctor if you had an allergic reaction to sulfa drugs (such as sulfamethoxazole).
  • Your doctor may want you to take your first dose in the doctor's office or clinic if you have heart disease.
  • Do not use this medicine to prevent migraine headaches, and do not use it to treat any other type of headache.
  • This medicine may cause the following problems:
    • Blurred vision or other vision changes
    • Heart problems
    • Sudden or severe abdominal or stomach pain or bloody diarrhea
  • This medicine may make you dizzy or drowsy. Do not drive or doing anything that could be dangerous until you know how this medicine affects you.
  • Call your doctor if your symptoms do not improve or if they get worse.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Blurred vision or other vision changes
  • Chest pain or shortness of breath
  • Fast, slow, or uneven heartbeat
  • Numbness or weakness in your arm or leg, or on one side of your body
  • Pain in your calf
  • Pain, tightness, or pressure in your chest, throat, neck, or jaw area
  • Pale, cool, or blotchy skin, numbness or tingling in the hands or feet
  • Problems with vision, speech, or walking
  • Severe stomach pain, bloody diarrhea

If you notice these less serious side effects, talk with your doctor:

  • Dizziness, drowsiness, or sleepiness
  • Dry mouth
  • Mild nausea or vomiting

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Version Info

  • Last reviewed on 8/4/2014

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